Reunion Neuroscience Inc. Appoints Greg Mayes as President and Chief Executive Officer

Reunion Neuroscience Inc. (TSX: REUN | NASDAQ: REUN), a leader in novel psychedelic drug development committed to innovating therapeutic solutions for mental health conditions by developing proprietary serotonin receptor agonist compounds, announced the appointment of Greg Mayes as President and Chief Executive Officer.

As Reunion’s new President and CEO, Mr. Mayes’ initial focus will be on the successful completion of the Company’s Phase 1 clinical trial with its lead asset, RE-104, a novel serotonergic psychedelic, which commenced in August 2022, and the planned launch of its Phase 2 study in postpartum depression, which is expected to commence in 2023. Mr. Mayes will also drive and accelerate Reunion’s preclinical RE-200 research, which is focused on the discovery of selective and specific serotonergic psychedelics.

Prior to joining Reunion, Mr. Mayes served in multiple C-Suite leadership roles at early-stage biotech and pharmaceutical companies, where he was integral in raising nearly half a billion dollars in investment capital and overseeing the successful completion of multiple early-phase FDA trials. As President and CEO of Antios Therapeutics, a clinical-stage biopharmaceutical company, Mayes led a $100+ million Series B financing with top healthcare investors in 2021. Prior to Antios, and inspired by his son’s epilepsy diagnosis, Mr. Mayes founded Engage Therapeutics, where he successfully raised $40 million in a Series A financing round led by TPG. He served as the Engage Therapeutics President and CEO from 2017 until 2020 when the company was acquired by UCB Pharma for $270 million, following a positive, randomized Phase 2b clinical trial evaluating its lead product candidate, a REST (Rapid Epileptic Seizure Termination) treatment.

Additionally, prior to founding Engage Therapeutics, Mr. Mayes played an integral role in the growth of Advaxis Immunotherapies (ADXS), a biotech company developing immuno-oncology therapies for patients with hard-to-treat cancers through its bacterial vector system. As Chief Operating Officer, he was instrumental in helping to secure more than $200 million in funding and in identifying and negotiating major pharmaceutical partnerships.

“Reunion is on the cusp of clinical breakthroughs and the Company needs leadership with experience in raising the capital we will need to get through the coming FDA trial process. With decades of experience in drug development, Greg brings an extensive wealth of knowledge and expertise at a pivotal time for Reunion,” said Joseph del Moral, Reunion’s Chairman. “As we complete our Phase 1 study with RE-104, Greg will help guide the Company to establish studies in postpartum and treatment-resistant depression. I am thrilled to welcome Greg and look forward to supporting him and Reunion as Chairman.”

It is anticipated that Mr. Mayes will be appointed to the Reunion Board of Directors to replace Ronan Levy, Reunion co-founder and current Chairman and CEO of Field Trip Health & Wellness Ltd., who will step down from Reunion’s Board in October 2022.

Reunion is a leader in novel psychedelic drug development, committed to innovating therapeutic solutions for mental health conditions by developing proprietary serotonin receptor agonist compounds. The Company’s lead asset, RE-104 (previously known as FT-104), is a proprietary, novel psychedelic drug being developed for post-partum and treatment resistant depression as a potential fast-acting antidepressant with durable efficacy. Reunion is also developing the FT-200 series, which includes compounds with potential for more selective serotonin receptor activity with reduced psychoactivity for potential use in more chronic treatment paradigms and indications.