Small Pharma Inc. (TSXV: DMT | OTCQB: DMTTF), a biotechnology company focused on short-acting psychedelic-assisted therapies for mental health conditions, today announces that as of October 18, 2022, it has been granted patent no. 11,471,417 by the United States Patent Office. This United States patent provides protection for a therapeutic composition of a small group of deuterated N,N-dimethyltryptamine (“DMT”) compounds, with expected lifetime of exclusivity until April 2041, further strengthening the Company’s intellectual property (“IP”) position in support of its research and development.

This patent sits alongside Small Pharma’s existing European granted patent no. 3902541, providing additional protection for the Company’s deuterated pipeline in a core market. The grant marks the Company’s twelfth granted patent in its psychedelic and non-psychedelic portfolio, which includes over 70 pending applications, and is the second United States patent grant within its psychedelic portfolio.

“We have made significant strides this year progressing our research and development programs and in securing key IP to support and protect them. We secured eight patent grants so far this year, bringing our total from four to twelve. The grant of this second United States patent effectively protects all pharmaceutical formulations of the specified deuterated DMT compounds, enabling us to progress our deuterated pipeline with even greater confidence.

George Tziras, Chief Executive Officer of Small Pharma,

About Small Pharma

Small Pharma is a biotechnology company progressing a pipeline of short-acting psychedelic assisted therapies for the treatment of mental health conditions. The Company’s current focus is on exploring new therapeutic approaches for depression. Small Pharma’s lead candidate, SPL026, is a proprietary synthetic formulation of DMT. The Company is advancing a clinical program of intravenous SPL026 with supportive therapy for the treatment of Major Depressive Disorder, which was granted an Innovation Passport designation from the U.K. Medicines and Healthcare products Regulatory Agency