Core One Labs Inc. (CSE: COOL | OTCQB: CLABF | Frankfurt: LD6 | WKN: A3CSSU) is pleased to announce that its wholly owned subsidiary Akome Biotech Ltd. through its formalized research agreement with Fundación Medina in Granada, Spain has received very encouraging results from pharmacokinetics studies currently underway. The study results represent another significant milestone in the Company’s pre-clinical development of its psychedelic based bioactive compounds designed to target Major Depressive Disorder, Stroke, Parkinson’s Disease and Alzheimer’s Disease, and warrant moving the formulations further along the development pipeline.
Pharmacokinetics studies the absorption, distribution, metabolism and excretion of drugs in humans, and also tests toxic effects of the drug candidate on body systems or organs. These studies are paramount in drug discovery and development as they de-risk drug candidate compounds and ultimately improve their productivity. When compounds are being developed for the treatment of neurologic and mental health disorders, it is also critical to determine the tissue concentration and behaviour in the brain of the candidate compounds, which is referred to as neuro-pharmacokinetics.
The very encouraging results from ADME/TOX neuro-pharmacokinetics studies, conducted by Fundación Medina, show that Akome’s bioactive compounds tested in controlled settings are performing very well, increasing the level of confidence scientists require for understanding the potential efficacy of Akome’s drug candidates, and moving our drug discovery process further along the development continuum towards regulatory approval.
“Core One’s scientists and research partners are achieving positive results at every stage of our pre-clinical drug trials, and we are thrilled with the progress that Akome is making in moving its psychedelic-based formulations along the development pipeline,” “The results presented today, combined with the positive bioassay results presented by the Company in April , demonstrate the significant potential our drug formulations hold. I am confident scientists at Akome, along with their research partners will continue to deliver strong results based on their track record of successes,”
Joel Shacker, Core One Labs CEO.
About Fundación Medina
Fundación Medina is an independent and non-profit renowned research center for innovative bio-pharmacology, and a reference center for natural products drug discovery. Its research activities are performed by a large group of multidisciplinary scientists in a state-of-the-art facility in Granada, Spain. Fundación Medina has extensive experience in drug discovery and focuses its research on high throughput screening programs in strategic therapeutic areas: infectious and parasitic diseases, oncology and neurodegeneration. Fundación Medina seeks discovery of new bioactive compounds and innovative therapies for unmet medical and industrial needs.
About Core One Labs Inc.
Core One is a biotechnology research and technology life sciences enterprise focused on bringing psychedelic medicines to market through novel delivery systems and psychedelic assisted psychotherapy. Core One has developed a patent pending thin film oral strip (the “technology”) which dissolves instantly when placed in the mouth and delivers organic molecules in precise quantities to the bloodstream, maintaining excellent bioavailability. The Company intends to further develop and apply the technology to psychedelic compounds, such as psilocybin. Core One also holds an interest in medical clinics which maintain a combined database of over 275,000 patients. Through these clinics, the integration of its intellectual property, R&D related to psychedelic treatments and novel drug therapies, the Company intends to obtain regulatory research approval for the advancement of psychedelic-derived treatments for mental health disorders.